One-shot NMR analysis of microbial secretions identifies highly potent proteasome inhibitor
One-shot NMR analysis of microbial secretions identifies highly potent proteasome inhibitor
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Natural products represent valuable lead structures for drug discovery. However, for most bioactive compounds no cellular target is yet identified and many substances predicted from genome analysis are inaccessible due to their life stage-dependent biosynthesis, which is not reflected in common isolation procedures. In response to these issues, an...
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Full title
One-shot NMR analysis of microbial secretions identifies highly potent proteasome inhibitor
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TN_cdi_pubmed_primary_23091006
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_23091006
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1211423109
