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Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the...

Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_23100531

Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis

About this item

Full title

Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2012-11, Vol.109 (46), p.18649-18650

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Although macrophages are widely recognized to have a profibrotic role in inflammation, we have used a highly tractable CCl 4 -induced model of reversible hepatic fibrosis to identify and characterize the macrophage phenotype responsible for tissue remodeling: the hitherto elusive restorative macrophage. This CD11B hi F4/80 int Ly-6C lo macrophage s...

Alternative Titles

Full title

Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_23100531

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_23100531

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1119964109

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