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Recombinant Human Bone Morphogenetic Protein Induces Bone Formation

Recombinant Human Bone Morphogenetic Protein Induces Bone Formation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_2315314

Recombinant Human Bone Morphogenetic Protein Induces Bone Formation

About this item

Full title

Recombinant Human Bone Morphogenetic Protein Induces Bone Formation

Publisher

United States: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 1990-03, Vol.87 (6), p.2220-2224

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

We have purified and characterized active recombinant human bone morphogenetic protein (BMP) 2A. Implantation of the recombinant protein in rats showed that a single BMP can induce bone formation in vivo. A dose-response and time-course study using the rat ectopic bone formation assay revealed that implantation of 0.5-115 μg of partially purified r...

Alternative Titles

Full title

Recombinant Human Bone Morphogenetic Protein Induces Bone Formation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_2315314

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_2315314

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.87.6.2220

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