Inhibition of α-helix-mediated protein–protein interactions using designed molecules
Inhibition of α-helix-mediated protein–protein interactions using designed molecules
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London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
α-Helix-mediated protein–protein interactions (PPIs) play a key role in the development of numerous infection and disease states. Modulating such interactions offers considerable therapeutic potential, however, identifying suitable inhibitors has proved challenging. This Review highlights recent and generic approaches for designing inhibitors of he...
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Full title
Inhibition of α-helix-mediated protein–protein interactions using designed molecules
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TN_cdi_pubmed_primary_23422557
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_23422557
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ISSN
1755-4330,1755-4349
E-ISSN
1755-4349
DOI
10.1038/nchem.1568
