Determination of dopamine D2 receptor occupancy by lurasidone using positron emission tomography in...
Determination of dopamine D2 receptor occupancy by lurasidone using positron emission tomography in healthy male subjects
About this item
Full title
Author / Creator
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Rationale
A positron emission tomography (PET) study of dopamine D
2
receptor occupancy was conducted to support a rational dose selection for clinical efficacy studies with lurasidone, an atypical antipsychotic that was approved for the treatment of schizophrenia by the FDA in late 2010.
Objectives
To determine the dopamine D
2
Alternative Titles
Full title
Determination of dopamine D2 receptor occupancy by lurasidone using positron emission tomography in healthy male subjects
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_23649882
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_23649882
Other Identifiers
ISSN
0033-3158
E-ISSN
1432-2072
DOI
10.1007/s00213-013-3103-z