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Determination of dopamine D2 receptor occupancy by lurasidone using positron emission tomography in...

Determination of dopamine D2 receptor occupancy by lurasidone using positron emission tomography in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_23649882

Determination of dopamine D2 receptor occupancy by lurasidone using positron emission tomography in healthy male subjects

About this item

Full title

Determination of dopamine D2 receptor occupancy by lurasidone using positron emission tomography in healthy male subjects

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Psychopharmacology, 2013-09, Vol.229 (2), p.245-252

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Rationale
A positron emission tomography (PET) study of dopamine D
2
receptor occupancy was conducted to support a rational dose selection for clinical efficacy studies with lurasidone, an atypical antipsychotic that was approved for the treatment of schizophrenia by the FDA in late 2010.
Objectives
To determine the dopamine D
2

Alternative Titles

Full title

Determination of dopamine D2 receptor occupancy by lurasidone using positron emission tomography in healthy male subjects

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_23649882

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_23649882

Other Identifiers

ISSN

0033-3158

E-ISSN

1432-2072

DOI

10.1007/s00213-013-3103-z

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