Aire-expressing thymic medullary epithelial cells originate from β5t-expressing progenitor cells
Aire-expressing thymic medullary epithelial cells originate from β5t-expressing progenitor cells
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
The thymus provides multiple microenvironments that are essential for the development and repertoire selection of T lymphocytes. The thymic cortex induces the generation and positive selection of T lymphocytes, whereas the thymic medulla establishes self-tolerance among the positively selected T lymphocytes. Cortical thymic epithelial cells (cTECs)...
Alternative Titles
Full title
Aire-expressing thymic medullary epithelial cells originate from β5t-expressing progenitor cells
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Record Identifier
TN_cdi_pubmed_primary_23720310
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_23720310
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1301799110
