Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic...
Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
We recently demonstrated that plectin is a robust biomarker for pancreatic ductal adenocarcinoma (PDAC), one of the most aggressive malignancies. In normal physiology, plectin is an intracellular scaffolding protein, but we have demonstrated localization on the extracellular surface of PDAC cells. In this study, we confirmed cell surface localizati...
Alternative Titles
Full title
Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer
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Record Identifier
TN_cdi_pubmed_primary_24218614
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_24218614
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1309720110
