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GRK3 is essential for metastatic cells and promotes prostate tumor progression

GRK3 is essential for metastatic cells and promotes prostate tumor progression

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_24434559

GRK3 is essential for metastatic cells and promotes prostate tumor progression

About this item

Full title

GRK3 is essential for metastatic cells and promotes prostate tumor progression

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2014-01, Vol.111 (4), p.1521-1526

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The biochemical mechanisms that regulate the process of cancer metastasis are still poorly understood. Because kinases, and the signaling pathways they comprise, play key roles in regulation of many cellular processes, we used an unbiased RNAi in vitro screen and a focused cDNA in vivo screen against human kinases to identify those with previously...

Alternative Titles

Full title

GRK3 is essential for metastatic cells and promotes prostate tumor progression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_24434559

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_24434559

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1320638111

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