GRK3 is essential for metastatic cells and promotes prostate tumor progression
GRK3 is essential for metastatic cells and promotes prostate tumor progression
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The biochemical mechanisms that regulate the process of cancer metastasis are still poorly understood. Because kinases, and the signaling pathways they comprise, play key roles in regulation of many cellular processes, we used an unbiased RNAi in vitro screen and a focused cDNA in vivo screen against human kinases to identify those with previously...
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Full title
GRK3 is essential for metastatic cells and promotes prostate tumor progression
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TN_cdi_pubmed_primary_24434559
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_24434559
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1320638111