Transcriptomics identified a critical role for Th2 cell-intrinsic miR-155 in mediating allergy and a...
Transcriptomics identified a critical role for Th2 cell-intrinsic miR-155 in mediating allergy and antihelminth immunity
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Allergic diseases, orchestrated by hyperactive CD4 ⁺ Th2 cells, are some of the most common global chronic diseases. Therapeutic intervention relies upon broad-scale corticosteroids with indiscriminate impact. To identify targets in pathogenic Th2 cells, we took a comprehensive approach to identify the microRNA (miRNA) and mRNA transcriptome of hig...
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Full title
Transcriptomics identified a critical role for Th2 cell-intrinsic miR-155 in mediating allergy and antihelminth immunity
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TN_cdi_pubmed_primary_25024218
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_25024218
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1406322111
