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Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition...

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_25082706

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

About this item

Full title

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

Publisher

United States

Journal title

Science (American Association for the Advancement of Science), 2014-08, Vol.345 (6196), p.1251343

Language

English

Formats

Publication information

Publisher

United States

More information

Scope and Contents

Contents

Long interspersed nuclear element-1 (L1) retrotransposons are mobile repetitive elements that are abundant in the human genome. L1 elements propagate through RNA intermediates. In the germ line, neighboring, nonrepetitive sequences are occasionally mobilized by the L1 machinery, a process called 3' transduction. Because 3' transductions are potenti...

Alternative Titles

Full title

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_25082706

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_25082706

Other Identifiers

E-ISSN

1095-9203

DOI

10.1126/science.1251343

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