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GATA2 facilitates steroid receptor coactivator recruitment to the androgen receptor complex

GATA2 facilitates steroid receptor coactivator recruitment to the androgen receptor complex

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_25489091

GATA2 facilitates steroid receptor coactivator recruitment to the androgen receptor complex

About this item

Full title

GATA2 facilitates steroid receptor coactivator recruitment to the androgen receptor complex

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (51), p.18261-18266

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The androgen receptor (AR) is a key driver of prostate cancer (PC), even in the state of castration-resistant PC (CRPC) and frequently even after treatment with second-line hormonal therapies such as abiraterone and enzalutamide. The persistence of AR activity via both ligand-dependent and ligand-independent mechanisms (including constitutively act...

Alternative Titles

Full title

GATA2 facilitates steroid receptor coactivator recruitment to the androgen receptor complex

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_25489091

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_25489091

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1421415111

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