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Molecular mechanism underlying β1 regulation in voltage- and calcium-activated potassium (BK) channe...

Molecular mechanism underlying β1 regulation in voltage- and calcium-activated potassium (BK) channe...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_25825713

Molecular mechanism underlying β1 regulation in voltage- and calcium-activated potassium (BK) channels

About this item

Full title

Molecular mechanism underlying β1 regulation in voltage- and calcium-activated potassium (BK) channels

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2015-04, Vol.112 (15), p.4809-4814

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Being activated by depolarizing voltages and increases in cytoplasmic Ca2+, voltage- and calcium-activated potassium (BK) channels and their modulatory β-subunits are able to dampen or stop excitatory stimuli in a wide range of cellular types, including both neuronal and nonneuronal tissues. Minimal alterations in BK channel function may contribute...

Alternative Titles

Full title

Molecular mechanism underlying β1 regulation in voltage- and calcium-activated potassium (BK) channels

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_25825713

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_25825713

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1504378112

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