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Dissecting enzyme function with microfluidic-based deep mutational scanning

Dissecting enzyme function with microfluidic-based deep mutational scanning

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_26040002

Dissecting enzyme function with microfluidic-based deep mutational scanning

About this item

Full title

Dissecting enzyme function with microfluidic-based deep mutational scanning

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2015-06, Vol.112 (23), p.7159-7164

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Significance As powerful biological catalysts, enzymes can solve challenging problems that range from the industrial production of chemicals to the treatment of human disease. The ability to design new enzymes with tailor-made chemical functions would have a far-reaching impact. However, this important capability has been limited by our cursory und...

Alternative Titles

Full title

Dissecting enzyme function with microfluidic-based deep mutational scanning

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_26040002

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_26040002

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1422285112

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