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Morin mitigates acetaminophen-induced liver injury by potentiating Nrf2 regulated survival mechanism...

Morin mitigates acetaminophen-induced liver injury by potentiating Nrf2 regulated survival mechanism...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_26286854

Morin mitigates acetaminophen-induced liver injury by potentiating Nrf2 regulated survival mechanism through molecular intervention in PHLPP2-Akt-Gsk3β axis

About this item

Full title

Morin mitigates acetaminophen-induced liver injury by potentiating Nrf2 regulated survival mechanism through molecular intervention in PHLPP2-Akt-Gsk3β axis

Publisher

New York: Springer US

Journal title

Apoptosis (London), 2015-10, Vol.20 (10), p.1296-1306

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Acetaminophen (APAP) is frequently taken to relieve pain. Staggered APAP overdoses have been reported to cause acetaminophen-induced liver injury (AILI). Identification of efficacious therapeutic modalities to address complications imposed by accidental/intentional long-term APAP ingestion is needed. Morin, a plant-derived phytochemical, possesses...

Alternative Titles

Full title

Morin mitigates acetaminophen-induced liver injury by potentiating Nrf2 regulated survival mechanism through molecular intervention in PHLPP2-Akt-Gsk3β axis

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_26286854

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_26286854

Other Identifiers

ISSN

1360-8185

E-ISSN

1573-675X

DOI

10.1007/s10495-015-1160-y

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