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Differential Modulation of Fast Inactivation in Cardiac Sodium Channel Splice Variants by Fyn Tyrosi...

Differential Modulation of Fast Inactivation in Cardiac Sodium Channel Splice Variants by Fyn Tyrosi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_26382759

Differential Modulation of Fast Inactivation in Cardiac Sodium Channel Splice Variants by Fyn Tyrosine Kinase

About this item

Full title

Differential Modulation of Fast Inactivation in Cardiac Sodium Channel Splice Variants by Fyn Tyrosine Kinase

Publisher

Basel, Switzerland: S. Karger AG

Journal title

Cellular Physiology and Biochemistry, 2015-09, Vol.37 (3), p.825-837

Language

English

Formats

Publication information

Publisher

Basel, Switzerland: S. Karger AG

More information

Scope and Contents

Contents

Background/Aims: Post-translational modifications such as phosphorylation and dephosphorylation can finely tune the function of ion channels. Na v 1.5 is the main sodium channel in human hearts and alternative splicing of the transcript generates two major splice variants, characterized by the presence (Q-pre) or absence (Q-del) of glutamine at pos...

Alternative Titles

Full title

Differential Modulation of Fast Inactivation in Cardiac Sodium Channel Splice Variants by Fyn Tyrosine Kinase

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_26382759

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_26382759

Other Identifiers

ISSN

1015-8987

E-ISSN

1421-9778

DOI

10.1159/000430211

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