Critical role of RAGE and HMGB1 in inflammatory heart disease
Critical role of RAGE and HMGB1 in inflammatory heart disease
About this item
Full title
Author / Creator
Bangert, Anna , Andrassy, Martin , Müller, Anna-Maria , Bockstahler, Mariella , Fischer, Andrea , Volz, Christian H. , Leib, Christoph , Göser, Stefan , Korkmaz-Icöz, Sevil , Zittrich, Stefan , Jungmann, Andreas , Lasitschka, Felix , Pfitzer, Gabriele , Müller, Oliver J. , Katus, Hugo A. and Kaya, Ziya
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Autoimmune response to cardiac troponin I (TnI) induces inflammation and fibrosis in the myocardium. High-mobility group box 1 (HMGB1) is a multifunctional protein that exerts proinflammatory activity by mainly binding to receptor for advanced glycation end products (RAGE). The involvement of the HMGB1–RAGE axis in the pathogenesis of inflammatory...
Alternative Titles
Full title
Critical role of RAGE and HMGB1 in inflammatory heart disease
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_26715748
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_26715748
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1522288113
