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Anti-myostatin antibody increases muscle mass and strength and improves insulin sensitivity in old m...

Anti-myostatin antibody increases muscle mass and strength and improves insulin sensitivity in old m...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_26858428

Anti-myostatin antibody increases muscle mass and strength and improves insulin sensitivity in old mice

About this item

Full title

Anti-myostatin antibody increases muscle mass and strength and improves insulin sensitivity in old mice

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2016-02, Vol.113 (8), p.2212-2217

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Sarcopenia, or skeletal muscle atrophy, is a debilitating comorbidity of many physiological and pathophysiological processes, including normal aging. There are no approved therapies for sarcopenia, but the antihypertrophic myokine myostatin is a potential therapeutic target. Here, we show that treatment of young and old mice with an anti-myostatin...

Alternative Titles

Full title

Anti-myostatin antibody increases muscle mass and strength and improves insulin sensitivity in old mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_26858428

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_26858428

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1525795113

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