Population-based 3D genome structure analysis reveals driving forces in spatial genome organization
Population-based 3D genome structure analysis reveals driving forces in spatial genome organization
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Conformation capture technologies (e.g., Hi-C) chart physical interactions between chromatin regions on a genome-wide scale. However, the structural variability of the genome between cells poses a great challenge to interpreting ensemble-averaged Hi-C data, particularly for long-range and interchromosomal interactions. Here, we present a probabilis...
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Full title
Population-based 3D genome structure analysis reveals driving forces in spatial genome organization
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TN_cdi_pubmed_primary_26951677
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_26951677
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1512577113
