Mutated Huntingtin Causes Testicular Pathology in Transgenic Minipig Boars
Mutated Huntingtin Causes Testicular Pathology in Transgenic Minipig Boars
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Author / Creator
Macakova, Monika , Bohuslavova, Bozena , Vochozkova, Petra , Pavlok, Antonin , Sedlackova, Miroslava , Vidinska, Daniela , Vochyanova, Klara , Liskova, Irena , Valekova, Ivona , Baxa, Monika , Ellederova, Zdenka , Klima, Jiri , Juhas, Stefan , Juhasova, Jana , Klouckova, Jana , Haluzik, Martin , Klempir, Jiri , Hansikova, Hana , Spacilova, Jana , Collins, Ryan , Blumenthal, Ian , Talkowski, Michael , Gusella, James F. , Howland, David S. , DiFiglia, Marian and Motlik, Jan
Publisher
Basel, Switzerland: S. Karger AG
Journal title
Language
English
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Publication information
Publisher
Basel, Switzerland: S. Karger AG
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Scope and Contents
Contents
Background: Huntington's disease is induced by CAG expansion in a single gene coding the huntingtin protein. The mutated huntingtin (mtHtt) primarily causes degeneration of neurons in the brain, but it also affects peripheral tissues, including testes. Objective: We studied sperm and testes of transgenic boars expressing the N-terminal region of hu...
Alternative Titles
Full title
Mutated Huntingtin Causes Testicular Pathology in Transgenic Minipig Boars
Authors, Artists and Contributors
Author / Creator
Bohuslavova, Bozena
Vochozkova, Petra
Pavlok, Antonin
Sedlackova, Miroslava
Vidinska, Daniela
Vochyanova, Klara
Liskova, Irena
Valekova, Ivona
Baxa, Monika
Ellederova, Zdenka
Klima, Jiri
Juhas, Stefan
Juhasova, Jana
Klouckova, Jana
Haluzik, Martin
Klempir, Jiri
Hansikova, Hana
Spacilova, Jana
Collins, Ryan
Blumenthal, Ian
Talkowski, Michael
Gusella, James F.
Howland, David S.
DiFiglia, Marian
Motlik, Jan
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_26959244
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_26959244
Other Identifiers
ISSN
1660-2854
E-ISSN
1660-2862
DOI
10.1159/000443665
