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Stimuli-responsive clustered nanoparticles for improved tumor penetration and therapeutic efficacy

Stimuli-responsive clustered nanoparticles for improved tumor penetration and therapeutic efficacy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_27035960

Stimuli-responsive clustered nanoparticles for improved tumor penetration and therapeutic efficacy

About this item

Full title

Stimuli-responsive clustered nanoparticles for improved tumor penetration and therapeutic efficacy

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2016-04, Vol.113 (15), p.4164-4169

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

A principal goal of cancer nanomedicine is to deliver therapeutics effectively to cancer cells within solid tumors. However, there are a series of biological barriers that impede nanomedicine from reaching target cells. Here, we report a stimuli-responsive clustered nanoparticle to systematically overcome these multiple barriers by sequentially res...

Alternative Titles

Full title

Stimuli-responsive clustered nanoparticles for improved tumor penetration and therapeutic efficacy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_27035960

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_27035960

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1522080113

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