The Interaction of Mitochondrial Biogenesis and Fission/Fusion Mediated by PGC-1α Regulates Rotenone...
The Interaction of Mitochondrial Biogenesis and Fission/Fusion Mediated by PGC-1α Regulates Rotenone-Induced Dopaminergic Neurotoxicity
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Author / Creator
Peng, Kaige , Yang, Likui , Wang, Jian , Ye, Feng , Dan, Guorong , Zhao, Yuanpeng , Cai, Ying , Cui, Zhihong , Ao, Lin , Liu, Jinyi , Zou, Zhongmin , Sai, Yan and Cao, Jia
Publisher
New York: Springer US
Journal title
Language
English
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Publication information
Publisher
New York: Springer US
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Contents
Parkinson’s disease is a common neurodegenerative disease in the elderly, and mitochondrial defects underlie the pathogenesis of PD. Impairment of mitochondrial homeostasis results in reactive oxygen species formation, which in turn can potentiate the accumulation of dysfunctional mitochondria, forming a vicious cycle in the neuron. Mitochondrial f...
Alternative Titles
Full title
The Interaction of Mitochondrial Biogenesis and Fission/Fusion Mediated by PGC-1α Regulates Rotenone-Induced Dopaminergic Neurotoxicity
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Record Identifier
TN_cdi_pubmed_primary_27271125
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_27271125
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ISSN
0893-7648
E-ISSN
1559-1182
DOI
10.1007/s12035-016-9944-9
