An essential role for the IL-2 receptor in T reg cell function
An essential role for the IL-2 receptor in T reg cell function
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Publisher
United States
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Language
English
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Publisher
United States
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Scope and Contents
Contents
Regulatory T cells (T
cells), which have abundant expression of the interleukin 2 receptor (IL-2R), are reliant on IL-2 produced by activated T cells. This feature indicates a key role for a simple network based on the consumption of IL-2 by T
cells in their suppressor function. However, congenital deficiency in IL-2R results in reduced expre...
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Full title
An essential role for the IL-2 receptor in T reg cell function
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Record Identifier
TN_cdi_pubmed_primary_27595233
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_27595233
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E-ISSN
1529-2916
DOI
10.1038/ni.3540