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An essential role for the IL-2 receptor in T reg cell function

An essential role for the IL-2 receptor in T reg cell function

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_27595233

An essential role for the IL-2 receptor in T reg cell function

About this item

Full title

An essential role for the IL-2 receptor in T reg cell function

Publisher

United States

Journal title

Nature immunology, 2016-11, Vol.17 (11), p.1322

Language

English

Formats

Publication information

Publisher

United States

More information

Scope and Contents

Contents

Regulatory T cells (T
cells), which have abundant expression of the interleukin 2 receptor (IL-2R), are reliant on IL-2 produced by activated T cells. This feature indicates a key role for a simple network based on the consumption of IL-2 by T
cells in their suppressor function. However, congenital deficiency in IL-2R results in reduced expre...

Alternative Titles

Full title

An essential role for the IL-2 receptor in T reg cell function

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_27595233

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_27595233

Other Identifiers

E-ISSN

1529-2916

DOI

10.1038/ni.3540

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