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Inhibitory Effects of Dopamine Receptor D 1 Agonist on Mammary Tumor and Bone Metastasis

Inhibitory Effects of Dopamine Receptor D 1 Agonist on Mammary Tumor and Bone Metastasis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_28374823

Inhibitory Effects of Dopamine Receptor D 1 Agonist on Mammary Tumor and Bone Metastasis

About this item

Full title

Inhibitory Effects of Dopamine Receptor D 1 Agonist on Mammary Tumor and Bone Metastasis

Publisher

England

Journal title

Scientific reports, 2017-04, Vol.7, p.45686

Language

English

Formats

Publication information

Publisher

England

More information

Scope and Contents

Contents

Dopaminergic signaling plays a critical role in the nervous system, but little is known about its potential role in breast cancer and bone metabolism. A screening of ~1,000 biologically active compounds revealed that a selective agonist of dopamine receptor D1 (DRD1), A77636, inhibited proliferation of 4T1.2 mammary tumor cells as well as MDA-MB-23...

Alternative Titles

Full title

Inhibitory Effects of Dopamine Receptor D 1 Agonist on Mammary Tumor and Bone Metastasis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_28374823

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_28374823

Other Identifiers

E-ISSN

2045-2322

DOI

10.1038/srep45686

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