Transient Receptor Potential Vanilloid 5 Mediates Ca2+ Influx and Inhibits Chondrocyte Autophagy in...
Transient Receptor Potential Vanilloid 5 Mediates Ca2+ Influx and Inhibits Chondrocyte Autophagy in a Rat Osteoarthritis Model
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Basel, Switzerland: Cell Physiol Biochem Press GmbH & Co KG
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English
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Basel, Switzerland: Cell Physiol Biochem Press GmbH & Co KG
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Background: Autophagy, a self-protective mechanism of chondrocytes, has become a promising target to impede the progress of osteoarthritis (OA). Autophagy is regulated by cytosolic Ca 2+ activity and may thus be modified by the Ca 2+ permeable transient receptor potential channel vanilloid 5 (TRPV5). Therefore, we investigated the potential role of...
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Transient Receptor Potential Vanilloid 5 Mediates Ca2+ Influx and Inhibits Chondrocyte Autophagy in a Rat Osteoarthritis Model
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TN_cdi_pubmed_primary_28535500
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_28535500
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ISSN
1015-8987
E-ISSN
1421-9778
DOI
10.1159/000477387
