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BAP1 regulates IP3R3-mediated Ca 2+ flux to mitochondria suppressing cell transformation

BAP1 regulates IP3R3-mediated Ca 2+ flux to mitochondria suppressing cell transformation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_28614305

BAP1 regulates IP3R3-mediated Ca 2+ flux to mitochondria suppressing cell transformation

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Publication information

Publisher

England

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Scope and Contents

Contents

BRCA1-associated protein 1 (BAP1) is a potent tumour suppressor gene that modulates environmental carcinogenesis. All carriers of inherited heterozygous germline BAP1-inactivating mutations (BAP1
) developed one and often several BAP1
malignancies in their lifetime, mostly malignant mesothelioma, uveal melanoma, and so on. Moreover, BAP1-acqu...

Alternative Titles

Full title

BAP1 regulates IP3R3-mediated Ca 2+ flux to mitochondria suppressing cell transformation

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Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_28614305

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_28614305

Other Identifiers

E-ISSN

1476-4687

DOI

10.1038/nature22798

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