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β 1 -adrenergic receptor O-glycosylation regulates N-terminal cleavage and signaling responses in ca...

β 1 -adrenergic receptor O-glycosylation regulates N-terminal cleavage and signaling responses in ca...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_28801655

β 1 -adrenergic receptor O-glycosylation regulates N-terminal cleavage and signaling responses in cardiomyocytes

About this item

Full title

β 1 -adrenergic receptor O-glycosylation regulates N-terminal cleavage and signaling responses in cardiomyocytes

Publisher

England

Journal title

Scientific reports, 2017-08, Vol.7 (1), p.7890

Language

English

Formats

Publication information

Publisher

England

More information

Scope and Contents

Contents

β
-adrenergic receptors (β
ARs) mediate catecholamine actions in cardiomyocytes by coupling to both Gs/cAMP-dependent and Gs-independent/growth-regulatory pathways. Structural studies of the β
AR define ligand-binding sites in the transmembrane helices and effector docking sites at the intracellular surface of the β
AR, but the extracel...

Alternative Titles

Full title

β 1 -adrenergic receptor O-glycosylation regulates N-terminal cleavage and signaling responses in cardiomyocytes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_28801655

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_28801655

Other Identifiers

E-ISSN

2045-2322

DOI

10.1038/s41598-017-06607-z

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