β 1 -adrenergic receptor O-glycosylation regulates N-terminal cleavage and signaling responses in ca...
β 1 -adrenergic receptor O-glycosylation regulates N-terminal cleavage and signaling responses in cardiomyocytes
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Author / Creator
Publisher
England
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Language
English
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Publisher
England
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Contents
β
-adrenergic receptors (β
ARs) mediate catecholamine actions in cardiomyocytes by coupling to both Gs/cAMP-dependent and Gs-independent/growth-regulatory pathways. Structural studies of the β
AR define ligand-binding sites in the transmembrane helices and effector docking sites at the intracellular surface of the β
AR, but the extracel...
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Full title
β 1 -adrenergic receptor O-glycosylation regulates N-terminal cleavage and signaling responses in cardiomyocytes
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TN_cdi_pubmed_primary_28801655
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_28801655
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E-ISSN
2045-2322
DOI
10.1038/s41598-017-06607-z