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Genomic upregulation of cardiac Cav1.2α and NCX1 by estrogen in women

Genomic upregulation of cardiac Cav1.2α and NCX1 by estrogen in women

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_28815011

Genomic upregulation of cardiac Cav1.2α and NCX1 by estrogen in women

About this item

Full title

Genomic upregulation of cardiac Cav1.2α and NCX1 by estrogen in women

Publisher

England

Journal title

Biology of sex differences, 2017, Vol.8, p.26

Language

English

Formats

Publication information

Publisher

England

More information

Scope and Contents

Contents

Women have a higher risk of lethal arrhythmias than men in long QT syndrome type 2 (LQTS2), but the mechanisms remain uncertain due to the limited availability of healthy control human tissue. We have previously reported that in female rabbits, estrogen increases arrhythmia risk in drug-induced LQTS2 by upregulating L-type Ca
(I
) and sodium-...

Alternative Titles

Full title

Genomic upregulation of cardiac Cav1.2α and NCX1 by estrogen in women

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_28815011

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_28815011

Other Identifiers

E-ISSN

2042-6410

DOI

10.1186/s13293-017-0148-4

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