Mettl3-/Mettl14-mediated mRNA N 6 -methyladenosine modulates murine spermatogenesis
Mettl3-/Mettl14-mediated mRNA N 6 -methyladenosine modulates murine spermatogenesis
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Author / Creator
Lin, Zhen , Hsu, Phillip J , Xing, Xudong , Fang, Jianhuo , Lu, Zhike , Zou, Qin , Zhang, Ke-Jia , Zhang, Xiao , Zhou, Yuchuan , Zhang, Teng , Zhang, Youcheng , Song, Wanlu , Jia, Guifang , Yang, Xuerui , He, Chuan and Tong, Ming-Han
Publisher
England
Journal title
Language
English
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Publisher
England
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Contents
Spermatogenesis is a differentiation process during which diploid spermatogonial stem cells (SSCs) produce haploid spermatozoa. This highly specialized process is precisely controlled at the transcriptional, posttranscriptional, and translational levels. Here we report that N
-methyladenosine (m
A), an epitranscriptomic mark regulating gene e...
Alternative Titles
Full title
Mettl3-/Mettl14-mediated mRNA N 6 -methyladenosine modulates murine spermatogenesis
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Record Identifier
TN_cdi_pubmed_primary_28914256
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_28914256
Other Identifiers
E-ISSN
1748-7838
DOI
10.1038/cr.2017.117
