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Endothelial GqPCR activity controls capillary electrical signaling and brain blood flow through PIP...

Endothelial GqPCR activity controls capillary electrical signaling and brain blood flow through PIP...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_29581272

Endothelial GqPCR activity controls capillary electrical signaling and brain blood flow through PIP 2 depletion

About this item

Full title

Endothelial GqPCR activity controls capillary electrical signaling and brain blood flow through PIP 2 depletion

Publisher

United States

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2018-04, Vol.115 (15), p.E3569

Language

English

Formats

Publication information

Publisher

United States

More information

Scope and Contents

Contents

Capillaries, the smallest blood vessels, mediate the on-demand delivery of oxygen and nutrients required to support the function of active cells throughout the brain. But how blood flow is directed to cells in active brain regions to satisfy their energy needs is poorly understood. We demonstrate that the plasma membrane phospholipid, PIP
2
,...

Alternative Titles

Full title

Endothelial GqPCR activity controls capillary electrical signaling and brain blood flow through PIP 2 depletion

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_29581272

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_29581272

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1800201115

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