MiR-27a Promotes Hemin-Induced Erythroid Differentiation of K562 Cells by Targeting CDC25B
MiR-27a Promotes Hemin-Induced Erythroid Differentiation of K562 Cells by Targeting CDC25B
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Author / Creator
Wang, Dongsheng , Si, Si , Wang, Qiang , Luo, Guangcheng , Du, Qin , Liang, Qi , Guo, Xiaolan , Zhang, Guoyuan , Feng, Jiafu and Leng, Zhengwei
Publisher
Basel, Switzerland: S. Karger AG
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Language
English
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Publisher
Basel, Switzerland: S. Karger AG
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Contents
Background/Aims: MicroRNAs (miRNAs) play a crucial role in erythropoiesis. MiR-23a∼27a∼24-2 clusters have been proven to take part in erythropoiesis via some proteins. CDC25B (cell division control Cdc2 phosphostase B) is also the target of mir-27a; whether it regulates erythropoiesis and its mechanism are unknown. Methods: To evaluate the potentia...
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Full title
MiR-27a Promotes Hemin-Induced Erythroid Differentiation of K562 Cells by Targeting CDC25B
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Record Identifier
TN_cdi_pubmed_primary_29590650
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_29590650
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ISSN
1015-8987
E-ISSN
1421-9778
DOI
10.1159/000488436