Identification of the allosteric P2X 7 receptor antagonist [ 11 C]SMW139 as a PET tracer of microgli...
Identification of the allosteric P2X 7 receptor antagonist [ 11 C]SMW139 as a PET tracer of microglial activation
About this item
Full title
Author / Creator
Janssen, Bieneke , Vugts, Danielle J , Wilkinson, Shane M , Ory, Dieter , Chalon, Sylvie , Hoozemans, Jeroen J M , Schuit, Robert C , Beaino, Wissam , Kooijman, Esther J M , van den Hoek, Johan , Chishty, Mansoor , Doméné, Aurélie , Van der Perren, Anke , Villa, Alessandro , Maggi, Adriana , Molenaar, Ger T , Funke, Uta , Shevchenko, Rostislav V , Baekelandt, Veerle , Bormans, Guy , Lammertsma, Adriaan A , Kassiou, Michael and Windhorst, Albert D
Publisher
England
Journal title
Language
English
Formats
Publication information
Publisher
England
Subjects
More information
Scope and Contents
Contents
The P2X
receptor plays a significant role in microglial activation, and as a potential drug target, the P2X
receptor is also an interesting target in positron emission tomography. The current study aimed at the development and evaluation of a potent tracer targeting the P2X
receptor, to which end four adamantanyl benzamide analogues with h...
Alternative Titles
Full title
Identification of the allosteric P2X 7 receptor antagonist [ 11 C]SMW139 as a PET tracer of microglial activation
Authors, Artists and Contributors
Author / Creator
Vugts, Danielle J
Wilkinson, Shane M
Ory, Dieter
Chalon, Sylvie
Hoozemans, Jeroen J M
Schuit, Robert C
Beaino, Wissam
Kooijman, Esther J M
van den Hoek, Johan
Chishty, Mansoor
Doméné, Aurélie
Van der Perren, Anke
Villa, Alessandro
Maggi, Adriana
Molenaar, Ger T
Funke, Uta
Shevchenko, Rostislav V
Baekelandt, Veerle
Bormans, Guy
Lammertsma, Adriaan A
Kassiou, Michael
Windhorst, Albert D
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_29700413
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_29700413
Other Identifiers
E-ISSN
2045-2322
DOI
10.1038/s41598-018-24814-0
