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Immune responses in the treatment of drug-sensitive pulmonary tuberculosis with phenylbutyrate and v...

Immune responses in the treatment of drug-sensitive pulmonary tuberculosis with phenylbutyrate and v...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_29973153

Immune responses in the treatment of drug-sensitive pulmonary tuberculosis with phenylbutyrate and vitamin D 3 as host directed therapy

About this item

Full title

Immune responses in the treatment of drug-sensitive pulmonary tuberculosis with phenylbutyrate and vitamin D 3 as host directed therapy

Publisher

England

Journal title

BMC infectious diseases, 2018-07, Vol.18 (1), p.303

Language

English

Formats

Publication information

Publisher

England

More information

Scope and Contents

Contents

We have previously shown that 8 weeks' treatment with phenylbutyrate (PBA) (500mgx2/day) with or without vitamin D
(vitD
) (5000 IU/day) as host-directed therapy (HDT) accelerated clinical recovery, sputum culture conversion and increased expression of cathelicidin LL-37 by immune cells in a randomized, placebo-controlled trial in adults with...

Alternative Titles

Full title

Immune responses in the treatment of drug-sensitive pulmonary tuberculosis with phenylbutyrate and vitamin D 3 as host directed therapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_29973153

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_29973153

Other Identifiers

E-ISSN

1471-2334

DOI

10.1186/s12879-018-3203-9

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