Role of mGlu2 in the 5-HT 2A receptor-dependent antipsychotic activity of clozapine in mice
Role of mGlu2 in the 5-HT 2A receptor-dependent antipsychotic activity of clozapine in mice
About this item
Full title
Role of mGlu2 in the 5-HT 2A receptor-dependent antipsychotic activity of clozapine in mice
Author / Creator
Publisher
Germany
Journal title
Psychopharmacology (Berlin, Germany), 2018-11, Vol.235 (11), p.3149
Language
English
Formats
Publication information
Publisher
Germany
Subjects
More information
Scope and Contents
Contents
Serotonin 5-HT
and metabotropic glutamate 2 (mGlu2) are neurotransmitter G protein-coupled receptors (GPCRs) involved in the signaling mechanisms underlying psychosis and schizophrenia treatment. Previous findings in mGlu2 knockout (KO) mice suggested that mGlu2 is necessary for head-twitch behavior, a rodent phenotype characteristic of hallucin...
Alternative Titles
Full title
Role of mGlu2 in the 5-HT 2A receptor-dependent antipsychotic activity of clozapine in mice
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_30209534
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_30209534
Other Identifiers
E-ISSN
1432-2072
DOI
10.1007/s00213-018-5015-4
