Endospanin 1 Determines the Balance of Leptin-Regulated Hypothalamic Functions
Endospanin 1 Determines the Balance of Leptin-Regulated Hypothalamic Functions
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Publisher
Basel, Switzerland: S. Karger AG
Journal title
Language
English
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Publisher
Basel, Switzerland: S. Karger AG
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Scope and Contents
Contents
Endospanin 1 (Endo1), a protein encoded in humans by the same gene than the leptin receptor (ObR), and increased by diet-induced obesity, is an important regulator of ObR trafficking and cell surface exposure, determining leptin signaling strength. Defective intracellular trafficking of the leptin receptor to the neuronal plasma membrane has been p...
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Full title
Endospanin 1 Determines the Balance of Leptin-Regulated Hypothalamic Functions
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Record Identifier
TN_cdi_pubmed_primary_30326479
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_30326479
Other Identifiers
ISSN
0028-3835
E-ISSN
1423-0194
DOI
10.1159/000494557
