Dopamine D 2 receptor occupancy of lumateperone (ITI-007): a Positron Emission Tomography Study in p...
Dopamine D 2 receptor occupancy of lumateperone (ITI-007): a Positron Emission Tomography Study in patients with schizophrenia
About this item
Full title
Author / Creator
Publisher
England
Journal title
Language
English
Formats
Publication information
Publisher
England
Subjects
More information
Scope and Contents
Contents
Dopamine D
receptor occupancy (D
RO) is a key feature of all currently approved antipsychotic medications. However, antipsychotic efficacy associated with high D
RO is often limited by side effects such as motor disturbances and hyperprolactinemia. Lumateperone (ITI-007) is a first-in-class selective and simultaneous modulator of serotonin...
Alternative Titles
Full title
Dopamine D 2 receptor occupancy of lumateperone (ITI-007): a Positron Emission Tomography Study in patients with schizophrenia
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_30449883
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_30449883
Other Identifiers
E-ISSN
1740-634X
DOI
10.1038/s41386-018-0251-1
