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A Light-Controlled Allosteric Modulator Unveils a Role for mGlu 4 Receptors During Early Stages of I...

A Light-Controlled Allosteric Modulator Unveils a Role for mGlu 4 Receptors During Early Stages of I...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_30542267

A Light-Controlled Allosteric Modulator Unveils a Role for mGlu 4 Receptors During Early Stages of Ischemia in the Rodent Cerebellar Cortex

About this item

Full title

A Light-Controlled Allosteric Modulator Unveils a Role for mGlu 4 Receptors During Early Stages of Ischemia in the Rodent Cerebellar Cortex

Publisher

Switzerland

Journal title

Frontiers in cellular neuroscience, 2018, Vol.12, p.449

Language

English

Formats

Publication information

Publisher

Switzerland

More information

Scope and Contents

Contents

Metabotropic glutamate receptors (mGlus) are G Protein coupled-receptors that modulate synaptic transmission and plasticity in the central nervous system. Some act as autoreceptors to control neurotransmitter release at excitatory synapses and have become attractive targets for drug therapy to treat certain neurological disorders. However, the high...

Alternative Titles

Full title

A Light-Controlled Allosteric Modulator Unveils a Role for mGlu 4 Receptors During Early Stages of Ischemia in the Rodent Cerebellar Cortex

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_30542267

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_30542267

Other Identifiers

ISSN

1662-5102

E-ISSN

1662-5102

DOI

10.3389/fncel.2018.00449

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