The in vivo specificity of synaptic Gβ and Gγ subunits to the α 2a adrenergic receptor at CNS synaps...
The in vivo specificity of synaptic Gβ and Gγ subunits to the α 2a adrenergic receptor at CNS synapses
About this item
Full title
The in vivo specificity of synaptic Gβ and Gγ subunits to the α 2a adrenergic receptor at CNS synapses
Author / Creator
Publisher
England
Journal title
Scientific reports, 2019-02, Vol.9 (1), p.1718
Language
English
Formats
Publication information
Publisher
England
More information
Scope and Contents
Contents
G proteins are major transducers of signals from G-protein coupled receptors (GPCRs). They are made up of α, β, and γ subunits, with 16 Gα, 5 Gβ and 12 Gγ subunits. Though much is known about the specificity of Gα subunits, the specificity of Gβγs activated by a given GPCR and that activate each effector in vivo is not known. Here, we examined the...
Alternative Titles
Full title
The in vivo specificity of synaptic Gβ and Gγ subunits to the α 2a adrenergic receptor at CNS synapses
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_30737458
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_30737458
Other Identifiers
E-ISSN
2045-2322
DOI
10.1038/s41598-018-37222-1
