Phosphate-induced ORAI1 expression and store-operated Ca 2+ entry in aortic smooth muscle cells
Phosphate-induced ORAI1 expression and store-operated Ca 2+ entry in aortic smooth muscle cells
About this item
Full title
Phosphate-induced ORAI1 expression and store-operated Ca 2+ entry in aortic smooth muscle cells
Author / Creator
Publisher
Germany
Journal title
Journal of molecular medicine (Berlin, Germany), 2019-10, Vol.97 (10), p.1465
Language
English
Formats
Publication information
Publisher
Germany
More information
Scope and Contents
Contents
Compromised renal phosphate elimination in chronic kidney disease (CKD) leads to hyperphosphatemia, which in turn triggers osteo-/chondrogenic signaling in vascular smooth muscle cells (VSMCs) and vascular calcification. Osteo-/chondrogenic transdifferentiation of VSMCs leads to upregulation of the transcription factors MSX2, CBFA1, and SOX9 as wel...
Alternative Titles
Full title
Phosphate-induced ORAI1 expression and store-operated Ca 2+ entry in aortic smooth muscle cells
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_31385016
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_31385016
Other Identifiers
E-ISSN
1432-1440
DOI
10.1007/s00109-019-01824-7
