Polarized PtdIns(4,5)P 2 distribution mediated by a voltage-sensing phosphatase (VSP) regulates sper...
Polarized PtdIns(4,5)P 2 distribution mediated by a voltage-sensing phosphatase (VSP) regulates sperm motility
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United States
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Language
English
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United States
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Voltage-sensing phosphatase (VSP) is a unique protein that consists of both the voltage-sensor domain and phosphoinositide phosphatase domain. In contrast with intensive studies on its molecular mechanisms, its physiological role has not been clear. Here, we report that VSP plays critical roles in mouse sperm motility. We found that VSP generates a...
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Full title
Polarized PtdIns(4,5)P 2 distribution mediated by a voltage-sensing phosphatase (VSP) regulates sperm motility
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TN_cdi_pubmed_primary_31776261
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_31776261
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1916867116