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Biological Evaluation, Molecular Docking, and SAR Studies of Novel 2-(2,4-Dihydroxyphenyl)-1 H - Ben...

Biological Evaluation, Molecular Docking, and SAR Studies of Novel 2-(2,4-Dihydroxyphenyl)-1 H - Ben...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_31842463

Biological Evaluation, Molecular Docking, and SAR Studies of Novel 2-(2,4-Dihydroxyphenyl)-1 H - Benzimidazole Analogues

About this item

Full title

Biological Evaluation, Molecular Docking, and SAR Studies of Novel 2-(2,4-Dihydroxyphenyl)-1 H - Benzimidazole Analogues

Publisher

Switzerland

Journal title

Biomolecules (Basel, Switzerland), 2019-12, Vol.9 (12)

Language

English

Formats

Publication information

Publisher

Switzerland

More information

Scope and Contents

Contents

In the present study, new 4-(1
-benzimidazol-2-yl)-benzene-1,3-diols, modified in both rings, have been synthesized and their efficacies as acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibitors have been determined. The modified Ellman's spectrophotometric method was applied for the biological evaluation. The compounds showed...

Alternative Titles

Full title

Biological Evaluation, Molecular Docking, and SAR Studies of Novel 2-(2,4-Dihydroxyphenyl)-1 H - Benzimidazole Analogues

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_31842463

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_31842463

Other Identifiers

E-ISSN

2218-273X

DOI

10.3390/biom9120870

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