Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholi...
Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholinesterase and butyrylcholinesterase reactivators
About this item
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Author / Creator
Publisher
England: Taylor & Francis
Journal title
Language
English
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Publication information
Publisher
England: Taylor & Francis
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Scope and Contents
Contents
The series of symmetrical and unsymmetrical isoquinolinium-5-carbaldoximes was designed and prepared for cholinesterase reactivation purposes. The novel compounds were evaluated for intrinsic acetylcholinesterase (AChE) or butyrylcholinesterase (BChE) inhibition, when the majority of novel compounds resulted with high inhibition of both enzymes and...
Alternative Titles
Full title
Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholinesterase and butyrylcholinesterase reactivators
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Record Identifier
TN_cdi_pubmed_primary_31910701
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_31910701
Other Identifiers
ISSN
1475-6366,1475-6374
E-ISSN
1475-6374
DOI
10.1080/14756366.2019.1710501
