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The sickle cell trait affects contact dynamics and endothelial cell activation in Plasmodium falcipa...

The sickle cell trait affects contact dynamics and endothelial cell activation in Plasmodium falcipa...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_31924859

The sickle cell trait affects contact dynamics and endothelial cell activation in Plasmodium falciparum-infected erythrocytes

About this item

Full title

The sickle cell trait affects contact dynamics and endothelial cell activation in Plasmodium falciparum-infected erythrocytes

Publisher

England

Journal title

Communications biology, 2018-11, Vol.1 (1), p.211

Language

English

Formats

Publication information

Publisher

England

More information

Scope and Contents

Contents

Sickle cell trait, a common hereditary blood disorder, protects carriers from severe disease in infections with the human malaria parasite Plasmodium falciparum. Protection is associated with a reduced capacity of parasitized erythrocytes to cytoadhere to the microvascular endothelium and cause vaso-occlusive events. However, the underpinning cellu...

Alternative Titles

Full title

The sickle cell trait affects contact dynamics and endothelial cell activation in Plasmodium falciparum-infected erythrocytes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_31924859

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_31924859

Other Identifiers

E-ISSN

2399-3642

DOI

10.1038/s42003-018-0223-3

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