Genetic Up-Regulation or Pharmacological Activation of the Na + /Ca 2+ Exchanger 1 (NCX1) Enhances H...
Genetic Up-Regulation or Pharmacological Activation of the Na + /Ca 2+ Exchanger 1 (NCX1) Enhances Hippocampal-Dependent Contextual and Spatial Learning and Memory
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Author / Creator
Natale, Silvia , Anzilotti, Serenella , Petrozziello, Tiziana , Ciccone, Roselia , Serani, Angelo , Calabrese, Lucrezia , Severino, Beatrice , Frecentese, Francesco , Secondo, Agnese , Pannaccione, Anna , Fiorino, Ferdinando , Cuomo, Ornella , Vinciguerra, Antonio , D'Esposito, Lucia , Sadile, Adolfo Gustavo , Cabib, Simona , Di Renzo, Gianfranco , Annunziato, Lucio and Molinaro, Pasquale
Publisher
United States
Journal title
Language
English
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Publication information
Publisher
United States
Subjects
More information
Scope and Contents
Contents
The Na
/Ca
exchanger 1 (NCX1) participates in the maintenance of neuronal Na
and Ca
homeostasis, and it is highly expressed at synapse level of some brain areas involved in learning and memory processes, including the hippocampus, cortex, and amygdala. Furthermore, NCX1 increases Akt1 phosphorylation and enhances glutamate-mediated Ca
Alternative Titles
Full title
Genetic Up-Regulation or Pharmacological Activation of the Na + /Ca 2+ Exchanger 1 (NCX1) Enhances Hippocampal-Dependent Contextual and Spatial Learning and Memory
Authors, Artists and Contributors
Author / Creator
Anzilotti, Serenella
Petrozziello, Tiziana
Ciccone, Roselia
Serani, Angelo
Calabrese, Lucrezia
Severino, Beatrice
Frecentese, Francesco
Secondo, Agnese
Pannaccione, Anna
Fiorino, Ferdinando
Cuomo, Ornella
Vinciguerra, Antonio
D'Esposito, Lucia
Sadile, Adolfo Gustavo
Cabib, Simona
Di Renzo, Gianfranco
Annunziato, Lucio
Molinaro, Pasquale
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_32048166
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_32048166
Other Identifiers
E-ISSN
1559-1182
DOI
10.1007/s12035-020-01888-4
