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PIK3R1 W624R Is an Actionable Mutation in High Grade Serous Ovarian Carcinoma

PIK3R1 W624R Is an Actionable Mutation in High Grade Serous Ovarian Carcinoma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_32075097

PIK3R1 W624R Is an Actionable Mutation in High Grade Serous Ovarian Carcinoma

Publication information

Publisher

Switzerland

More information

Scope and Contents

Contents

Identifying cancer drivers and actionable mutations is critical for precision oncology. In epithelial ovarian cancer (EOC) the majority of mutations lack biological or clinical validation. We fully characterized 43 lines of Patient-Derived Xenografts (PDXs) and performed copy number analysis and whole exome sequencing of 12 lines derived from naïve...

Alternative Titles

Full title

PIK3R1 W624R Is an Actionable Mutation in High Grade Serous Ovarian Carcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_32075097

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_32075097

Other Identifiers

E-ISSN

2073-4409

DOI

10.3390/cells9020442

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