Bax inhibitor-1 deficiency leads to obesity by increasing Ca 2+ -dependent insulin secretion
Bax inhibitor-1 deficiency leads to obesity by increasing Ca 2+ -dependent insulin secretion
About this item
Full title
Bax inhibitor-1 deficiency leads to obesity by increasing Ca 2+ -dependent insulin secretion
Author / Creator
Publisher
Germany
Journal title
Journal of molecular medicine (Berlin, Germany), 2020-06, Vol.98 (6), p.849
Language
English
Formats
Publication information
Publisher
Germany
More information
Scope and Contents
Contents
Transmembrane BAX inhibitor motif containing 6 (TMBIM6), also known as Bax inhibitor-1, is an evolutionarily conserved protein involved in endoplasmic reticulum (ER) function. TMBIM6 is an ER Ca
leak channel and its deficiency enhances susceptibility to ER stress due to inhibition of the ER stress sensor IRE1α. It was previously shown that TMBIM...
Alternative Titles
Full title
Bax inhibitor-1 deficiency leads to obesity by increasing Ca 2+ -dependent insulin secretion
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_32394396
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_32394396
Other Identifiers
E-ISSN
1432-1440
DOI
10.1007/s00109-020-01914-x
