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Flightless-1 inhibits ER stress-induced apoptosis in colorectal cancer cells by regulating Ca 2+ hom...

Flightless-1 inhibits ER stress-induced apoptosis in colorectal cancer cells by regulating Ca 2+ hom...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_32504039

Flightless-1 inhibits ER stress-induced apoptosis in colorectal cancer cells by regulating Ca 2+ homeostasis

About this item

Full title

Flightless-1 inhibits ER stress-induced apoptosis in colorectal cancer cells by regulating Ca 2+ homeostasis

Publisher

United States

Journal title

Experimental & molecular medicine, 2020-06, Vol.52 (6), p.940

Language

English

Formats

Publication information

Publisher

United States

More information

Scope and Contents

Contents

The endoplasmic reticulum (ER) stress response is an adaptive mechanism that is activated upon disruption of ER homeostasis and protects the cells against certain harmful environmental stimuli. However, critical and prolonged cell stress triggers cell death. In this study, we demonstrate that Flightless-1 (FliI) regulates ER stress-induced apoptosi...

Alternative Titles

Full title

Flightless-1 inhibits ER stress-induced apoptosis in colorectal cancer cells by regulating Ca 2+ homeostasis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_32504039

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_32504039

Other Identifiers

E-ISSN

2092-6413

DOI

10.1038/s12276-020-0448-3

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