Impairment of spatial memory accuracy improved by Cbr1 copy number resumption and GABA B receptor-de...
Impairment of spatial memory accuracy improved by Cbr1 copy number resumption and GABA B receptor-dependent enhancement of synaptic inhibition in Down syndrome model mice
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England
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English
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England
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Down syndrome is a complex genetic disorder caused by the presence of three copies of the chromosome 21 in humans. The most common models, carrying extra-copies of overlapping fragments of mouse chromosome 16 that is syntenic to human chromosome 21, are Ts2Cje, Ts1Cje and Ts1Rhr mice. In electrophysiological analyses using hippocampal slices, we fo...
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Impairment of spatial memory accuracy improved by Cbr1 copy number resumption and GABA B receptor-dependent enhancement of synaptic inhibition in Down syndrome model mice
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TN_cdi_pubmed_primary_32843708
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_32843708
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E-ISSN
2045-2322
DOI
10.1038/s41598-020-71085-9
