Isoform-specific Activities of Androgen Receptor and its Splice Variants in Prostate Cancer Cells
Isoform-specific Activities of Androgen Receptor and its Splice Variants in Prostate Cancer Cells
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United States
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English
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United States
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Androgen receptor (AR) signaling continues to drive castration-resistant prostate cancer (CRPC) in spite of androgen deprivation therapy (ADT). Constitutively active shorter variants of AR, lacking the ligand binding domain, are frequently expressed in CRPC and have emerged as a potential mechanism for prostate cancer to escape ADT. ARv7 and ARv567...
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Isoform-specific Activities of Androgen Receptor and its Splice Variants in Prostate Cancer Cells
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TN_cdi_pubmed_primary_33508110
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_33508110
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E-ISSN
1945-7170
DOI
10.1210/endocr/bqaa227