FX11 limits Mycobacterium tuberculosis growth and potentiates bactericidal activity of isoniazid thr...
FX11 limits Mycobacterium tuberculosis growth and potentiates bactericidal activity of isoniazid through host-directed activity
About this item
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Author / Creator
Publisher
England
Journal title
Language
English
Formats
Publication information
Publisher
England
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Scope and Contents
Contents
Lactate dehydrogenase A (LDHA) mediates interconversion of pyruvate and lactate and increased lactate turnover is exhibited by malignant and infected immune cells. Hypoxic lung granuloma in Mycobacterium tuberculosis-infected animals present elevated levels of Ldha and lactate. Such alterations in the metabolic milieu could influence the outcome of...
Alternative Titles
Full title
FX11 limits Mycobacterium tuberculosis growth and potentiates bactericidal activity of isoniazid through host-directed activity
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Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_34005000
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_34005000
Other Identifiers
E-ISSN
1754-8411
DOI
10.1242/dmm.041954
