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Spatio-temporal biodistribution of 89 Zr-oxine labeled huLym-1-A-BB3z-CAR T-cells by PET imaging in...

Spatio-temporal biodistribution of 89 Zr-oxine labeled huLym-1-A-BB3z-CAR T-cells by PET imaging in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_34302002

Spatio-temporal biodistribution of 89 Zr-oxine labeled huLym-1-A-BB3z-CAR T-cells by PET imaging in a preclinical tumor model

About this item

Full title

Spatio-temporal biodistribution of 89 Zr-oxine labeled huLym-1-A-BB3z-CAR T-cells by PET imaging in a preclinical tumor model

Publisher

England

Journal title

Scientific reports, 2021-07, Vol.11 (1), p.15077

Language

English

Formats

Publication information

Publisher

England

More information

Scope and Contents

Contents

Quantitative in vivo monitoring of cell biodistribution offers assessment of treatment efficacy in real-time and can provide guidance for further optimization of chimeric antigen receptor (CAR) modified cell therapy. We evaluated the utility of a non-invasive, serial
Zr-oxine PET imaging to assess optimal dosing for huLym-1-A-BB3z-CAR T-cell dir...

Alternative Titles

Full title

Spatio-temporal biodistribution of 89 Zr-oxine labeled huLym-1-A-BB3z-CAR T-cells by PET imaging in a preclinical tumor model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_34302002

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_34302002

Other Identifiers

E-ISSN

2045-2322

DOI

10.1038/s41598-021-94490-0

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